ارزیابی کارایی واکسن آبله طیور موسسه رازی در پولت تخمگذار

نوع مقاله : مقاله کامل

نویسندگان

1 بخش تحقیق و تولید واکسن های ویروسی طیور، موسسه تحقیقات واکسن و سرم سازی رازی، سازمان تحقیقات، آموزش و ترویج کشاورزی، کرج، ایرانکشاورزی، کرج، ایران

2 بخش تحقیق و تولید واکسن های ویروسی طیور، موسسه تحقیقات واکسن و سرم سازی رازی، سازمان تحقیقات، آموزش و ترویج کشاورزی، کرج، ایران

چکیده

موثرترین راه پیشگیری بیماری آبله طیور واکسیناسیون می‌باشد و هدف از انجام این مطالعه تعیین میزان ایمنی ایجاد شده توسط واکسن آبله طیور موسسه رازی و  نیز مشخص نمودن کارایی واکسن مذکور در مقابل عامل بیماری‌زا می‌باشد. مطالعه حاضر در دو مرحله شامل واکسیناسیون جوجه‌های تحت آزمایش در فارم و مرحله دوم شامل آزمایش چالش بود که  در پولت‌های واکسینه شده انجام گرفت. بدین منظور جوجه‌های یک سالن شصت هزارتایی پولت نژاد مرغ تخمگذار بونز (Bovans) با واکسن آبله طیور موسسه رازی به روش تلقیح در پرده بال واکسینه شدند. هفت تا  10 روز پس از انجام واکسیناسیون پاسخ گله به واکسن با بررسی %10 کل سالن مرغداری صورت پذیرفت و میزان وجود  Take % 7/96 بود. جهت  آزمایش چالش در دو گروه پولت 30 تایی در دو سالن مجزا که گروه اول شامل پولت واکسینه و گروه دوم که واکسنی دریافت نکرده بودند ویروس آبله تلقیح شد. گروه شاهد همگی علائم بیماری ولی تمام پرندگان گروه واکسینه فاقد علائم بیماری بودند. نتایج این مطالعه نشان داد که واکسن آبله موسسه رازی دارای ایمنیت و کارایی بسیار بالایی می‌باشد.

کلیدواژه‌ها

عنوان مقاله [English]

Efficacy evaluation of Razi Institute Fowl pox vaccine in laying hen pullet

نویسندگان [English]

  • A. Alemian 1
  • B. Khalesi 2
  • M. M. Ebrahimi 2
  • Sh. Masoudi 2
1 Master of Science Lab, Department of Research and Production of Poultry Viral Vaccine, Razi Vaccine and Serum Research institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran
2 Assistant Professor, Department of Research and Production of Poultry Viral Vaccine, Razi Vaccine and Serum Research institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran.
چکیده [English]

The most effective way to prevent fowl pox disease is to vaccinate and the aim of this study was to determine the immunity level of fowl pox vaccine and also to determine the efficacy of the vaccine against the pathogenic agent, which seems necessary and important to do so. The experiments of this study are summarized in two sections. The first stage includes the vaccination of the experienced chicks in the farm and the evaluation of the effect of the vaccine on the farm, and the second phase included a challenge test carried out in the vaccinated pullets. In order to realize this, fowl pox vaccine of the Razi Institute, which is live attenuated, was inoculated into a curtain under the wing in a layer flock with sixty thousands of Bowans strain laying hen farm was used for testing. Seven to ten days after vaccination, the immune response of the herd was investigated in 10% of the layer flock was taken and the percentage was 96.7%. Then, in order to the challenge test, 30 of these pullets were divided into two separate halls, the first group consisting of vaccinated pullets and the second group that did not inoculate the vaccine. The pathogenic virus was inoculated to them and the control group showed all the symptoms of the disease, and all the birds in the control group had no symptoms. From the above experiments, it is concluded that fowl pox vaccine of the Razi Institute has suitable efficacy.

کلیدواژه‌ها [English]

  • Fowl pox vaccine
  • Razi institute
  • Evaluation of the immunity
  • challenge

مراجع

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تحقیقات دامپزشکی و فرآورده‌های بیولوژیک
دوره 34، شماره 1
فروردین 1400
صفحه 6-14

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سابقه مقاله

  • تاریخ دریافت: 10 دی 1397
  • تاریخ بازنگری: 30 دی 1398
  • تاریخ پذیرش: 03 اسفند 1398

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