عنوان مقاله [English]
The objectives of this field trial was to compare the effects of clinical endometritis treament in dairy cows with either: Ceftiofur, Cloprostenol or Theranekron in 21-33 DIM. Clinical endometritis was defined as the presence of purulent/muco-purulent discharge and/or cervical diameter >7.5 cm and PMN concentration ≥18% in cytological samples. Eighty cows with clinical endometritis were assigned randomly into 4 groups. Group 1 cows received 3 consecutive doses of Ceftiofur (1 mg/kg IM; Excenel), in 3 days. Group 2 animals received 2 doses of Cloprostenol on days 1 and 14. Group 3 cows received two SC injections of Theranekron (10 mg/Cow) on days 1 and 10. Group 4 received no treatment. Inflammatory cells were collected by cytobrush. In order to dignose cows suffering from clinical endometritis, first cytobrush sample was taken before starting protocols and PMN cells were collecte, the second sample was taken 3 days after the last injection. All treatment protocols caused a favorable response, although response to Theranekron was more prominent than Ceftiofur (p<0.05). A decrease in PMN% was shown in group 2 and 3 in the samples (p<0.05), but not in group 1 animals (p>0.05). A decrease in the diameter of external os was found in all groups even in the control cows but it was more preminent in Teranekron group (p<0.05). Theranekron, caused improvements in clinical and cytological sings of endometritis (p<0.05). In conclusion in this study, systemic treatment of postpartum endometritis in cattle with Theranekron and PGF2α was effective to reduce inflammation.
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