بررسی تاثیر بیهوشی با پروپوفول بر برخی فاکتورهای بیوشیمیایی سرم خون ماهی کپور علفخوار، Ctenopharyngodon idella

نویسندگان

1 استاد، گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه شهید چمران اهواز

2 دانشیار، گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه شهید چمران اهواز

3 دانش آموخته دانشکده دامپزشکی دانشگاه شهید چمران اهواز

چکیده

به منظور بررسی اثر غلظت های مختلف داروی بیهوشی پروپوفول بر برخی پارامترهای بیوشیمیایی سرم خون، تعداد 120 قطعه ماهی کپور علفخوار به دو روش غوطه وری و تزریق داخل وریدی بیهوش گردیدند. از ماهی ها در حین بیهوشی و 4 روز پس از آن خون گیری به عمل آمد. در روش غوطه وری میانگین میزان پتاسیم در همه غلظت ها و میانگین مقدار اوره و ازت اوره خون در غلظت 4 میلی گرم بر لیتر در حین بیهوشی با پروپوفول به ترتیب بطور معنی داری بیشتر و کمتر از گروه شاهد بودند. در این روش غلظت کلسیم، فسفر، پتاسیم و کلسترول در زمان بیهوشی و 4 روز پس از آن تفاوت معنی دار داشتند. در روش تزریق داخل وریدی میانگین غلظت کلسیم و میانگین مقدار کلر، سدیم و پتاسیم در حین بیهوشی با پروپوفول به ترتیب بطور معنی داری کمتر و بیشتر از گروه شاهد بودند. در 4 روز پس از بیهوشی نیز میانگین میزان سدیم و پتاسیم افزایش معنی داری در مقایسه با گروه شاهد داشت. بطور کلی به نظر می رسد پروپوفول تاثیر قابل توجهی بر فاکتورهای بیوشیمیایی خون ماهی مورد مطالعه داشت اگر چه تغییرات مشاهده شده عموماً در محدوده طبیعی و قابل قبول قرار دارد.

عنوان مقاله [English]

Effect of anesthesia with propofol on biochemical parameters of serum in grass carp (Ctenopharyngodon idella)

نویسندگان [English]

  • R Peyghan 1
  • G.H Khadjeh 1
  • H Nadaf 2
  • S Larki 3
1 Professor, Clinical Sciences Department, Veterinary Faculty, Shahid Chamran University of Ahvaz, Ahvaz-Iran.
2 Associate Professor, Clinical Sciences Department, Veterinary Faculty, Shahid Chamran University of Ahvaz, Ahvaz-Iran
3 Graduated Student, Veterinary Faculty, Shahid Chamran University. Ahvaz-Iran
چکیده [English]

In this study for determinination of effects of anesthesia with propofol on some of biochemical factors of blood, 120 grass carp were chosen. The fish were exposed to the ascending concentration of propofol by bath method and injection method. At the time of anesthesia and 4 days after anesthesia blood samples were taken from the caudal vein and some biochemical parameters of blood were measured and compared. At anesthesia with propofol, in bath method the mean of potassium was significantly higher than the control group. At the time of anesthesia the mean of phosphorus, blood urea nitrogen (BUN) and urea were significantly lower than the control group and in 4 days after anesthesia. The mean of calcium, phosphorus and cholesterol were significantly lower than the control group. The mean of calcium, phosphorus and cholesterol at the time of anesthesia were significantly higher than their means in 4 days after anesthesia whith propofol, but the mean of potassium at the time of anesthesia was significantly lower than their mean in 4 days after anesthesia. At the time of anesthesia with propofol, in injection method the mean of sodium and potassium, cholorid were significantly higher than the control group and in 4 days after anesthesia the mean of sodium and potassium were significantly higher than the control group. These results showed that propofol have had a markrd effect on biochemichal factores of blood serum, however the changes had been in normal range for the studied factors.

 

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