عنوان مقاله [English]
Molecular dynamic (MD) simulation is a knowledge which uses combination of biological sciences, chemistry, and various computer / mathematical methods and algorithms. This technique is applied in advanced design of drugs, vaccines, antibodies, proteins/peptides, and other macro and micro molecules of infectious / non-infectious agents as well as substances. The ever-increasing progress in this field of bioinformatics for the design and manufacture of ultra-advanced biological and pharmaceutical products helps to simulate the in vitro biological phenomena similar to the in vivo conditions. Introducing this science from practical and productive points of view to researchers who are working in universities or medical and veterinary institues can make them more familiar with this progressive field of science, and is effective on improvment researchs and production. On the other hand, the use of this knowlage reduces the excess cost and time of production. This paper, firstly discusses the introduction and division of MD in a general view, and then discusses the basic content and advantages of MD, and finally discusses the methods and programs used therein. The last section of the paper has addressed the use of this new method in immunoinformatic research (design of vaccin, kit, antibody, adjuvant, etc.), chemoinformatics (drug design), and also investigation of infectious diseases..
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