عنوان مقاله [English]
Due to the increasing resistance of pathogenic bacteria to antibiotics, finding a natural antimicrobial agent is important as an alternative drug. The European foulbrood disease is one of the common diseases in apiaries and Peniacillus alvei is one of the disease-causing bacteria. In this study, antibacterial effects of some products of honeybee (propolis, honey) were tested on Peniacillus alvei. For this purpose, the needed products of hive were collected from numbers of different areas in Kerman state and were extracted in the lab. Then, Penibacillus alvei was cultivated in special medium and affected by different concentrations of the extracts. Finally, MIC and MBC of samples were determined by disc diffusion and microtiter plate tests. The data were analyzed by SAS software. Although, the results showed that the antibacterial effect of water and alcoholic extracts of propolis and honey was lower than the usual standard antibiotics (P<0.01), their antibacterial effect was significant on inhibition and lethality of Penibacillus alvei. Ethanol and methanol extracts of propolis had inhibitory and lethal effects on Penibacillus alvei at a concentration of 0.32 mg/ml, but honey had inhibitory and lethal effects on this bacteria at none of the tested concentrations. The results showed that propolis has an antibacterial effect on the causative agent of European foulbrood disease in honeybee.
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